Tag: Abigail Powers
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Myotube and endothelial cell coculture optimization to determine the effect of DM1 on angiogenesis
By Emily Boyd, Abigail Powers Faculty Mentor: Dr. Ginny Morriss Abstract Myotonic Dystrophy Type 1 (DM1) is an autosomal dominant disorder caused by CTG repeats and results in muscle wasting. Increased concentration and inactivation of platelet derived growth factor receptor-β (PDGFRβ) has been reported in a mouse model of DM1 and in DM1 patient muscles.…
